Syntheses of 1,2-Amino Alcohols and Their Applications for Oxazaborolidine-Catalyzed Enantioselective Reduction of Aromatic Ketones.
โ Scribed by Namdev S. Vatmurge; Braja G. Hazra; Vandana S. Pore
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 41 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract In the presence of tridentate chiral ligand **4e**, 99% e.e. value was obtained by asymmetric reduction of ethyl benzoylacetate with borane in toluene at 25ยฐC. Various ligands and reaction conditions were investigated to develop a reasonable mechanism that explains the experimental outc
The ab initio molecular orbital method is employed to study the structures and properties of chiral cyclic sulfur-containing oxazaborolidine, as a catalyst, and its borane adducts. All the structures are optimized completely by means of the Hartree-Fock method at 6-31g \* basis sets. The catalyst is
An Optimized in situ Procedure for the Oxazaborolidine Catalyzed Enantioselective Reduction of Prochiral Ketones. -The catalyst prepared from (S)-diphenyl prolinol is found to be the best amongst several other analogues for the reduction of alkyl aryl ketones. -(PRASAD, K. R.