Our second generation strategy for the total synthesis of brevetoxin A involved dissection of the molecule at the ring F oxocene. Synthetically, the F ring formation was expected to occur through Wittig coupling of requisite polycyclic fragments 2 and 3, followed by a hydroxy dithioketal cyclization
β¦ LIBER β¦
ChemInform Abstract: Total Synthesis of Brevetoxin A. Part 2. Second Generation Strategy and Construction of EFGH Model System.
β Scribed by K. C. Nicolaou; Paul A. Wallace; Shuhao Shi; Michael A. Ouellette; Mark E. Bunnage; Janet L. Gunzner; Konstantinos A. Agrios; Guo-qiang Shi; Peter Gaertner; Zhen Yang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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