Synthesis and Biological Evaluation of α,α-Difluorobenzylphosphonic Acid Derivatives as Small Molecular Inhibitors of Protein-Tyrosine Phosphatase 1B. -Title compounds (V) and (XI) are prepared by a Stille coupling reaction sequence. It is shown that desired inhibitory activity towards protein-tyro
✦ LIBER ✦
ChemInform Abstract: Preparation of Chiral α-Monofluoroalkylphosphonic Acids and Their Evaluation as Inhibitors of Protein Tyrosine Phosphatase 1B.
✍ Scribed by Christopher C. Kotoris; Wendy Wen; Alan Lough; Scott D. Taylor
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
ChemInform Abstract: Synthesis and Biolo
✍
Tsutomu Yokomatsu; Tetsuo Murano; Ikuko Umesue; Shinji Soeda; Hiroshi Shimeno; S
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 34 KB
👁 1 views
α,α-Difluoro-β-ketophosphonates as Poten
✍
Xianfeng Li; Ashok Bhandari; Christopher P. Holmes; Anna K. Szardenings
📂
Article
📅
2004
🏛
John Wiley and Sons
⚖ 24 KB
👁 1 views
## Abstract For Abstract see ChemInform Abstract in Full Text.
ChemInform Abstract: New Azolidinediones
✍
Michael S. Malamas; Janet Sredy; Iwan Gunawan; Brenda Mihan; Diane R. Sawicki; L
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 35 KB
ChemInform Abstract: Novel Benzofuran an
✍
Michael S. Malamas; et al. et al.
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 29 KB
👁 1 views
ChemInform Abstract: Naphthalenebis[α,α-
✍
Q. WANG; Z. HUANG; C. RAMACHANDRAN; A. N. DINAUT; S. D. TAYLOR
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 29 KB
👁 1 views
Naphthalenebis [α,α-difluoromethylenephosphonates] as Potent Inhibitors of Protein Tyrosine Phosphatases. -The desired disubstituted naphthalenes are better protein tyrosine phosphatase inhibitors than the monosubstituted ones. Derivatives (I)-(III) are the most potent inhibitors yet reported. -(WA
ChemInform Abstract: Synthesis and Evalu
✍
Samer Haidar; Christian D. P. Klein; Rolf W. Hartmann
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 32 KB
👁 1 views