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ChemInform Abstract: Naphthalenebis[α,α-difluoromethylenephosphonates] as Potent Inhibitors of Protein Tyrosine Phosphatases.

✍ Scribed by Q. WANG; Z. HUANG; C. RAMACHANDRAN; A. N. DINAUT; S. D. TAYLOR

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Naphthalenebis [α,α-difluoromethylenephosphonates] as Potent Inhibitors of Protein Tyrosine Phosphatases.

-The desired disubstituted naphthalenes are better protein tyrosine phosphatase inhibitors than the monosubstituted ones. Derivatives (I)-(III) are the most potent inhibitors yet reported. -(WANG, Q.;

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