ChemInform Abstract: Asymmetric Synthesis of a C-3 Substituted Pipecolic Acid.
β Scribed by Andrew J. Souers; Jonathan A. Ellman
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
The synthesis of two enantiopure pipecolic acid esters (VI) and (XIII) is reported. Key steps are the intramolecular addition of allyl silane on an iminium double bond, generated via reaction of chiral Ξ²-amino alcohols (I) and (VII), with glyoxal (II).