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Characterization of the submicroscopic deletion in the small-cell lung carcinoma (SCLC) cell line U2020

Book ID
122574120
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
152 KB
Volume
10
Category
Article
ISSN
0169-5002

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πŸ“œ SIMILAR VOLUMES

Characterization of the submicroscopic d
Characterization of the submicroscopic deletion in the small-cell lung carcinoma (SCLC) cell line U2020
✍ Dr. Harry A. Drabkin; Mike J. Mendez; Pamela H. Rabbitts; Terry Varkony; Jonas B πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 673 KB

The small-cell lung carcinoma cell line U2020 contains a submicroscopic, homozygous deletion that removes a chromosomal segment within 3p 13-p 14, including the locus D3S3. W e have sublocalized 49 additional probes to the 3p 13-p 14.2 region and have identified 7 new D N A markers that arise from w

A submicroscopic homozygous deletion at
A submicroscopic homozygous deletion at the D3S3 locus in a cell line isolated from a small cell lung carcinoma
✍ Dr. Pamela Rabbitts; Jonas Bergh; Jenny Douglas; Francis Collins; Jonathan Water πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 691 KB

We have used 14 DNA probes, which detect 19 different restriction enzyme length polymorphisms, t o search for heterozygosity on chromosome 3 in five cell lines isolated from patients with small cell lung carcinoma. The cell lines on karyotype analysis did not show the deletion in chromosome 3 charac

Molecular characterization of a large ho
Molecular characterization of a large homozygous deletion in the small cell lung cancer cell line U2020: A strategy for cloning the putative tumor suppressor gene
✍ Farida Latif; Kalman Tory; William S. Modi; Stephen L. Graziano; Gary Gamble; Je πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 844 KB

## Abstract Homozygous deletions are instrumental in the detection and cloning of tumor suppressor genes. We report the isolation and characterization of 39 new single‐copy probes saturating a submicroscopic homozygous deletion detected in the DNA of the small cell lung cancer (SCLC) cell line U202