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A submicroscopic homozygous deletion at the D3S3 locus in a cell line isolated from a small cell lung carcinoma

Book ID
122972207
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
161 KB
Volume
7
Category
Article
ISSN
0169-5002

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A submicroscopic homozygous deletion at
A submicroscopic homozygous deletion at the D3S3 locus in a cell line isolated from a small cell lung carcinoma
โœ Dr. Pamela Rabbitts; Jonas Bergh; Jenny Douglas; Francis Collins; Jonathan Water ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 691 KB

We have used 14 DNA probes, which detect 19 different restriction enzyme length polymorphisms, t o search for heterozygosity on chromosome 3 in five cell lines isolated from patients with small cell lung carcinoma. The cell lines on karyotype analysis did not show the deletion in chromosome 3 charac

Characterization of the submicroscopic d
Characterization of the submicroscopic deletion in the small-cell lung carcinoma (SCLC) cell line U2020
โœ Dr. Harry A. Drabkin; Mike J. Mendez; Pamela H. Rabbitts; Terry Varkony; Jonas B ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 673 KB

The small-cell lung carcinoma cell line U2020 contains a submicroscopic, homozygous deletion that removes a chromosomal segment within 3p 13-p 14, including the locus D3S3. W e have sublocalized 49 additional probes to the 3p 13-p 14.2 region and have identified 7 new D N A markers that arise from w