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Molecular characterization of a large homozygous deletion in the small cell lung cancer cell line U2020: A strategy for cloning the putative tumor suppressor gene


Book ID
122648415
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
152 KB
Volume
10
Category
Article
ISSN
0169-5002

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Molecular characterization of a large ho
✍ Farida Latif; Kalman Tory; William S. Modi; Stephen L. Graziano; Gary Gamble; Je πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 844 KB

## Abstract Homozygous deletions are instrumental in the detection and cloning of tumor suppressor genes. We report the isolation and characterization of 39 new single‐copy probes saturating a submicroscopic homozygous deletion detected in the DNA of the small cell lung cancer (SCLC) cell line U202