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Frequent loss of heterozygosity in region of the KIP1 locus in non-small cell lung cancer: Evidence for a new tumor suppressor gene on the short arm of chromosome 12


Book ID
121914989
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
136 KB
Volume
15
Category
Article
ISSN
0169-5002

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Deletions involving the chromosome 9p21 region have been reported as frequent events in non-small cell lung cancer (NSCLC). To investigate potential tumor-suppressor gene (TSG) loci within the 9p21 region, which also harbors the candidate TSG locus CDKN2a, we studied 32 cases of primary NSCLC for lo