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Microsatellite instability and loss of heterozygosity at the hMLH1 locus on chromosome 3p21 occur in a subset of non-small cell lung carcinomas


Book ID
123054074
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
132 KB
Volume
15
Category
Article
ISSN
0169-5002

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Deletions involving the chromosome 9p21 region have been reported as frequent events in non-small cell lung cancer (NSCLC). To investigate potential tumor-suppressor gene (TSG) loci within the 9p21 region, which also harbors the candidate TSG locus CDKN2a, we studied 32 cases of primary NSCLC for lo