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Characterization of synthetic retinoids with selectivity for retinoic acid or retinoid X nuclear receptors

✍ Scribed by Peter K LeMotte; Siegfried Keidel; Christian M Apfel

Book ID
116126960
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
656 KB
Volume
1289
Category
Article
ISSN
0304-4165

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## Abstract The first step in retinoid action is binding to their nuclear receptors. Therefore, characterization of binding characteristics of retinoids is of major importance. Human retinoic acid receptors Ξ± (hRARΞ±), hRARΞ², and mouse RARΞ³ (mRARΞ³) were expressed heterologously in __Escherichia coli