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Distinct modes of interaction of the retinoic acid receptor alpha with natural and synthetic retinoids

✍ Scribed by Bruno Lefebvre; Arnaud Mouchon; Pierre Formstecher; Philippe Lefebvre


Book ID
117463964
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
150 KB
Volume
139
Category
Article
ISSN
0303-7207

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## Abstract The first step in retinoid action is binding to their nuclear receptors. Therefore, characterization of binding characteristics of retinoids is of major importance. Human retinoic acid receptors Ξ± (hRARΞ±), hRARΞ², and mouse RARΞ³ (mRARΞ³) were expressed heterologously in __Escherichia coli