Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
✍ Scribed by Kliewer, Steven A.; Umesono, Kazuhiko; Mangelsdorf, David J.; Evans, Ronald M.
- Book ID
- 109779528
- Publisher
- Nature Publishing Group
- Year
- 1992
- Tongue
- English
- Weight
- 636 KB
- Volume
- 355
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/355446a0
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## Abstract Abstract vitamin D receptor (VDR) and retinoid X receptor (RXR) heterodimerize to mediate the genomic actions of 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~, calcitriol), the biologically active form of vitamin D~3~. In this study, we show that 9‐__cis__ retinoic acid (9‐cisRA), the l