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Critical role of both retinoid nuclear receptors and retinoid-X-receptors in mediating growth inhibition of ovarian cancer cells by all-trans retinoic acid

✍ Scribed by Wu, Shujian; Zhang, Dongmei; Zhang, Zhen-Ping; Soprano, Dianne Robert; Soprano, Kenneth J


Book ID
110061679
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
579 KB
Volume
17
Category
Article
ISSN
0950-9232

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In order to better understand the mechanisms that underlie the antiproliferative effect of retinoids, we have examined the response of human carcinoma cell lines to all-trans retinoic acid (RA) and N-(4-hydroxyphenyl) retinamide (4HPR) in terms of cell growth, apoptosis and regulation of retinoic ac