𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of O6-methylguanine-DNA-methyltransferase (O6-MGMT) activity in Xiphophorus fishes

✍ Scribed by Ronald B Walter; Huang-Mo Sung; Gabe W Intano; Christi A Walter


Book ID
117766718
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
241 KB
Volume
493
Category
Article
ISSN
1383-5718

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Differential inactivation of O6-methylgu
✍ Katsuyoshi Mineura; Masahito Fukuchi; Masayoshi Kowada; Isamu Terashima; Kohfuku πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 473 KB

Activity of 06-methylguanine-DNA methyltransferase (MGMT) is well related with drug resistance of tumor cells to chloroethylnitrosoureas (CENUs), because MGMT removes CENU-induced O6-alkyIguanines in DNA by accepting the alkyl group at a cysteine moiety. Inactivation of MGMT is a feasible way to ove