𝔖 Bobbio Scriptorium
✦   LIBER   ✦

O6-methylguanine DNA methyltransferase activity in diabetic patients

✍ Scribed by Tülay Akçay; Yıldız Dinçer; Nilgün Çelebi; Hasan İlkova


Book ID
117370669
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
196 KB
Volume
61
Category
Article
ISSN
0168-8227

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Differential inactivation of O6-methylgu
✍ Katsuyoshi Mineura; Masahito Fukuchi; Masayoshi Kowada; Isamu Terashima; Kohfuku 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 473 KB

Activity of 06-methylguanine-DNA methyltransferase (MGMT) is well related with drug resistance of tumor cells to chloroethylnitrosoureas (CENUs), because MGMT removes CENU-induced O6-alkyIguanines in DNA by accepting the alkyl group at a cysteine moiety. Inactivation of MGMT is a feasible way to ove