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Biomimetic synthesis of dibromophakellin

โœ Scribed by Foley, Louise H.; Buechi, George


Book ID
127366888
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
289 KB
Volume
104
Category
Article
ISSN
0002-7863

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Total Synthesis of (+)-Dibromophakellin
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## Abstract **Two members of a family** of pyrroleโ€“imidazole marine alkaloids, (+)โ€dibromophakellin and the nonnatural congener (+)โ€phakellin, were synthesized enantioselectively from 4โ€hydroxyโ€Lโ€proline. The chiral aminal at C10 was constructed efficiently by means of an Overmanโ€type [3,3] sigmatr