𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Beyond the locus control region: new light on β-globin locus regulation

✍ Scribed by Xing-Guo Li; De-Pei Liu; Chih-chuan Liang

Book ID
117755691
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
92 KB
Volume
33
Category
Article
ISSN
1357-2725

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Locus control region mediated regulation
Locus control region mediated regulation of adult β-globin gene expression
✍ Shermi Liang; Babak Moghimi; Thomas P. Yang; John Strouboulis; Jörg Bungert 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB

## Abstract Many genes residing in gene clusters and expressed in a differentiation or developmental‐stage specific manner are regulated by locus control regions (LCRs). These complex genetic regulatory elements are often composed of several DNAse I hypersensitive sites (HS sites) that function tog

Both locus control region and proximal r
Both locus control region and proximal regulatory elements direct the developmental regulation of β-globin gene cluster
✍ Xin-jun Ji; De-pei Liu; Dong-dong Xu; Lei Li; Jing Wang; Chih-chuan Liang 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB

Using ligation-mediated PCR and in vivo footprinting methods to study the status of DNA-protein interaction at hypersensitive site 2 of locus control region and ␤ maj promoter of erythroid cells of fetal liver and adult bone marrow, we found that during different developmental periods, the status of