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Deletions within the Mouse β-Globin Locus Control Region Preferentially Reduce βmin Globin Gene Expression

✍ Scribed by Raouf Alami; M.A. Bender; Yong-Qing Feng; Steven N. Fiering; Bruce A. Hug; Timothy J. Ley; Mark Groudine; Eric E. Bouhassira

Book ID
115615022
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
179 KB
Volume
63
Category
Article
ISSN
0888-7543

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## Abstract Many genes residing in gene clusters and expressed in a differentiation or developmental‐stage specific manner are regulated by locus control regions (LCRs). These complex genetic regulatory elements are often composed of several DNAse I hypersensitive sites (HS sites) that function tog