Asymmetric reduction of α,β-unsaturated ketones with Bakers' yeast1
✍ Scribed by Yasushi Kawai; Kentarou Saitou; Kouichi Hida; Atsuyoshi Ohno
- Book ID
- 108036327
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 117 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
A novel carbon-carbon double-bond reductase was isolated from the cells of baker's yeast. The reduction of c~,[~-unsaturated ketones catalyzed by this enzyme affords the corresponding saturated (S)-ketones selectively.
Two chiral nitro alcohols, (S)-4-nitro-2-butanol and (S)-S-nitro-2pentanol were prepared enantioselectively by reduction of the corresponding ketones with bakers' yeast. Utility of organic nitro compounds as synthetic intermediates has been well established. 1) Namely, the nitro group has facility
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