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Asymmetric reduction of α,β-unsaturated ketones with Bakers' yeast1

✍ Scribed by Yasushi Kawai; Kentarou Saitou; Kouichi Hida; Atsuyoshi Ohno


Book ID
108036327
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
117 KB
Volume
6
Category
Article
ISSN
0957-4166

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Asymmetric reduction of α,β-unsaturated
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A novel carbon-carbon double-bond reductase was isolated from the cells of baker's yeast. The reduction of c~,[~-unsaturated ketones catalyzed by this enzyme affords the corresponding saturated (S)-ketones selectively.

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Two chiral nitro alcohols, (S)-4-nitro-2-butanol and (S)-S-nitro-2pentanol were prepared enantioselectively by reduction of the corresponding ketones with bakers' yeast. Utility of organic nitro compounds as synthetic intermediates has been well established. 1) Namely, the nitro group has facility

ChemInform Abstract: Asymmetric Reductio
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v