𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Apoptosis is directly related to intracellular amyloid accumulation in a cell line derived from the cerebral cortex of a trisomy 16 mouse, an animal model of Down syndrome

✍ Scribed by Christian Arriagada; Miguel Bustamante; Illani Atwater; Eduardo Rojas; Raúl Caviedes; Pablo Caviedes


Book ID
116771990
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
515 KB
Volume
470
Category
Article
ISSN
0304-3940

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Knockdown of amyloid precursor protein n
✍ Patricia Opazo; Katherine Saud; Michelle de Saint Pierre; Ana María Cárdenas; Da 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 307 KB

## Abstract We have generated immortal neuronal cell lines from normal and trisomy 16 (Ts16) mice, a model for Down syndrome (DS). Ts16 lines overexpress DS‐related genes (__App__, amyloid precursor protein; __Sod1__, Cu/Zn superoxide dismutase) and show altered cholinergic function (reduced cholin