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Apolipoprotein E Genotype and Early Alzheimer's Disease: A Longitudinal SPECT Study

✍ Scribed by Shigeki Sakamoto; Hiroshi Matsuda; Takashi Asada; Takashi Ohnishi; Seigo Nakano; Hidekazu Kanetaka; Masaru Takasaki

Book ID
109266877
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
177 KB
Volume
13
Category
Article
ISSN
1051-2284

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## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with early‐onset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) early‐onset non‐VG families showing evidence of linkage