Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans
β Scribed by Dr. H. C. Hendrie; K. S. Hall; S. Hui; F. W. Unverzagt; C. E. Yu; D. K. Lahiri; A. Sahota; M. Farlow; B. Musick; A. Brashear; V. E. Burdine; B. O. Osuntokun; A. O. Ogunniyi; O. Gureje; O. Baiyewu; G. D. Schellenberg
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 327 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0364-5134
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## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with earlyβonset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) earlyβonset nonβVG families showing evidence of linkage
seen at our Stroke Service and Stroke Clinic so as to minimize bias of nonrandom sampling. We attempted to obtain routinely many of the laboratory tests that may be abnormal in association with aCL; however, every patient did not have every study performed routinely. We conclude that a larger, cont