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Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease

โœ Scribed by Dr Sandro Sorbi; Benedetta Nacmias; Paolo Forleo; Silvia Piacentini; Stefania Latorraca; Luigi Amaducci


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
389 KB
Volume
38
Category
Article
ISSN
0364-5134

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โœฆ Synopsis


seen at our Stroke Service and Stroke Clinic so as to minimize bias of nonrandom sampling. We attempted to obtain routinely many of the laboratory tests that may be abnormal in association with aCL; however, every patient did not have every study performed routinely.

We conclude that a larger, controlled, prospective study of recurrent stroke and thrombo-occlusive event risk attributable to aPL is warranted. The recently initiated collaboration of the Warfarin Aspirin Recurrent Stroke Study (WARSS) and the Antiphospholipid Antibodies and Stroke Study (APASS) groups should provide these data. 15. Rosove MH, Brewer PMC. Antiphospholipid thrombosis: clinical course after the first thrombotic event in 70 patients. Ann


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Background. Anticholinesterase therapies oer modest beneยฎt to subgroups of AD suerers. However, there has previously been no way of predicting which patients will respond to any of the drugs. Objective. To discover if gender and/or apolipoprotein E genotype can be used as predictors of response in