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Apolipoprotein E and alzheimer's disease: Ethnic variation in genotypic risks

✍ Scribed by Gladys Maestre; Ruth Ottman; Yaakov Stern; Barry Gurland; Michael Chun; Ming-Xin Tang; Michael Shelanski; Benjamin Tycko; Richard Mayeux


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
654 KB
Volume
37
Category
Article
ISSN
0364-5134

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## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with early‐onset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) early‐onset non‐VG families showing evidence of linkage