Apolipoprotein E and alzheimer's disease: Ethnic variation in genotypic risks
β Scribed by Gladys Maestre; Ruth Ottman; Yaakov Stern; Barry Gurland; Michael Chun; Ming-Xin Tang; Michael Shelanski; Benjamin Tycko; Richard Mayeux
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 654 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Recent studies have 'found an association between presence of apolipoprotein E (APOE) β¬4 allele and Alzheimer's disease (AD). The present study compared the cumulative risk of primary progressive dementia (PPD) in relatives of AD probands carrying at least one copy of the β¬4 allele with the relative
## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with earlyβonset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) earlyβonset nonβVG families showing evidence of linkage