Antibody a c t i v i t y t o various histones was examined i n a s o l i d phase radioimmunoassay. More than one h a l f o f the sera from systemic lupus erythematosus (SLE) p a t i e n t s had IgM a c t i v i t y t o t o t a l histones, and a s l i g h t l y lower frequency was observed f o r IgG a
Anti–topoisomerase I (Anti–Scl-70) antibodies in patients with systemic lupus erythematosus
✍ Scribed by Hélène A. Elicha Gussin; Georghe P. Ignat; John Varga; Marius Teodorescu
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 426 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Annexin V has a calcium-dependent binding affinity for anionic phospholipids and activated platelets, and prevents prothrombinase activity. We investigated the clinical significance of IgG anti-annexin V antibodies in patients with SLE. The study population consisted of 140 patients with SLE. Sera w
## Abstract We investigated anti‐annexin V antibody (aANX) in patients with systemic lupus erythe‐matosus (SLE), and correlated to positivity with lupus anticoagulant (LA)/anticardiolipin antibody (aCL). aANX was positive in 12/47 SLE patients (26%), including 7 with β~2~‐glycoprotein 1 (GPl)‐depen
## Abstract Twenty‐one sera from 11 patients with systemic lupus erythematosus were titrated with ^125^I‐ss‐calf thymus DNA to determine their maximum capacity to bind DNA. Only five sera were capable of binding > 90% of the input DNA. The remaining sixteen sera showed maximum DNA binding levels be