Correlation of anti-Ro antibody with photosensitivity rash in systemic lupus erythematosus patients
โ Scribed by Chaim B. Mond; Margaret G. E. Peterson; Naomi F. Rothfield
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 250 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0004-3591
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๐ SIMILAR VOLUMES
## Abstract We investigated antiโannexin V antibody (aANX) in patients with systemic lupus erytheโmatosus (SLE), and correlated to positivity with lupus anticoagulant (LA)/anticardiolipin antibody (aCL). aANX was positive in 12/47 SLE patients (26%), including 7 with ฮฒ~2~โglycoprotein 1 (GPl)โdepen
Annexin V has a calcium-dependent binding affinity for anionic phospholipids and activated platelets, and prevents prothrombinase activity. We investigated the clinical significance of IgG anti-annexin V antibodies in patients with SLE. The study population consisted of 140 patients with SLE. Sera w
To characterize the initial events in anti-Ro production by a patient with systemic lupus erythematosus, in whom this autoantibody is developing. Methods. The immune response to the Ro ribonucleoprotein and other autoantigens were studied by enzyme-linked immunosorbent assay for IgG and IgM, by iso