✦ LIBER ✦

Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody

✍ Scribed by Dr. Juzo Matsuda; Noriko Saitoh; Kengo Gohchi; Moritaka Gotoh; And Miyo Tsukamoto

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 185 KB
Volume: 47
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.2830470112

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We investigated anti‐annexin V antibody (aANX) in patients with systemic lupus erythe‐matosus (SLE), and correlated to positivity with lupus anticoagulant (LA)/anticardiolipin antibody (aCL). aANX was positive in 12/47 SLE patients (26%), including 7 with β~2~‐glycoprotein 1 (GPl)‐dependent aANX. The positivity of aANX was higher in patients with aCL (19%) and LA/aCL (50%) than in those without LA/aCL (10%). From these results, it is concluded that aANX is an autoantibody closely related to LA/aCL, and can be a possible new risk marker for thrombosis. © 1994 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Clinical significance of anti-annexin V

Clinical significance of anti-annexin V antibodies in patients with systemic lupus erythematosus

✍ Kaburaki, Junichi; Kuwana, Masataka; Yamamoto, Mihoko; Kawai, Shinichi; Ikeda, Y 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 82 KB 👁 2 views

Annexin V has a calcium-dependent binding affinity for anionic phospholipids and activated platelets, and prevents prothrombinase activity. We investigated the clinical significance of IgG anti-annexin V antibodies in patients with SLE. The study population consisted of 140 patients with SLE. Sera w

Anti-annexin V antibodies in plasma and

Anti-annexin V antibodies in plasma and serum samples from patients with lupus anticoagulant

✍ Chie Kuragaki; Kinichi Kidoguchi; Norihiko Nakamura; Yoshinao Wada 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 2 views

Antibody to annexin V has anti-phospholi

Antibody to annexin V has anti-phospholipid and lupus anticoagulant properties

✍ Norihiko Nakamura; Chie Kuragaki; Yoshihiro Shidara; Kenji Yamaji; Yoshinao Wada 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB 👁 1 views

HLA-DR antigens and anticardiolipin anti

HLA-DR antigens and anticardiolipin antibodies in patients with systemic lupus erythematosus

✍ Neil J. McHugh; Peter J. Maddison; M. Savi; G. F. Ferraccioli; T. M. Neri; P. Za 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB 👁 2 views

Lupus anticoagulant,anti-ro (ss-a) antib

Lupus anticoagulant,anti-ro (ss-a) antibodies, and fetal wastage in system lupus erythematosus

✍ Osvaldo Hubscher; Alicia Eimon; Roberto M. Arana; Dardo A. Riveros 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 255 KB 👁 1 views

Limited Anti-DNA Antibody Specificity in

Limited Anti-DNA Antibody Specificity in Systemic Lupus Erythematosus

✍ Ronald N. Berzofsky; Carole A. Dorsch; Mary Betty Stevens 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 477 KB 👁 2 views

## Abstract Twenty‐one sera from 11 patients with systemic lupus erythematosus were titrated with ^125^I‐ss‐calf thymus DNA to determine their maximum capacity to bind DNA. Only five sera were capable of binding > 90% of the input DNA. The remaining sixteen sera showed maximum DNA binding levels be