Anti-?2-glycoprotein I antibodies in pediatric systemic lupus erythematosus and antiphospholipid syndrome
β Scribed by von Scheven, Emily ;Glidden, David V. ;Elder, Melissa E.
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 129 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
Antibody a c t i v i t y t o various histones was examined i n a s o l i d phase radioimmunoassay. More than one h a l f o f the sera from systemic lupus erythematosus (SLE) p a t i e n t s had IgM a c t i v i t y t o t o t a l histones, and a s l i g h t l y lower frequency was observed f o r IgG a
## Objective: To determine the frequency of mutations in the phospholipid binding domain of beta2-glycoprotein i (beta2gpi) in patients with systemic lupus erythematosus (sle) and/or antiphospholipid syndrome (aps), and to analyze the clinical correlations of such mutations with thromboembolic comp