An evolutionary concept for changes of synovial tissue innervation in patients with rheumatoid arthritis
β Scribed by R. H. Straub; H. O. Besedovsky
- Book ID
- 110754998
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 323 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0906-6705
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## Abstract Markedly elevated levels of T cells expressing Ia antigens were found in the synovial membranes and synovial fluids of patients with rheumatoid arthritis. The primary increase in expression of the la antigens was on the OKT 8+ (suppressor/cytotoxic) T cell subset. In addition, the total
## Abstract ## Objective To find evidence for the presence of endothelial precursor cells, which can induce new vessel formation, in the synovial tissue of patients with rheumatoid arthritis (RA) and osteoarthritis (OA). ## Methods Precursor cells in the synovial tissue of 18 RA patients and 15
Cytogenetic analysis of primary cell cultures and/or passages 1-3 of synovial tissue from seven patients with rheumatoid arthritis was performed. As the only recurrent chromosome aberration, trisomy 7 was found in six of seven cultures. In four cultures, trisomy 7 occurred as a clonal change in up t