Objective. A causative role for Epstein-Barr virus (EBV) in the development of lymphoma in patients with rheumatoid arthritis (RA) has been proposed. We investigated the molecular features of EBV-positive diffuse large cell lymphomas in 2 patients with RA. Methods. Southern blot analysis for immuno
Lytic Epstein-Barr virus infection in the synovial tissue of patients with rheumatoid arthritis
β Scribed by Tsuyoshi Takeda; Yuzo Mizugaki; Lina Matsubara; Shosuke Imai; Takao Koike; Kenzo Takada
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 1022 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0004-3591
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Lack of Epstein-Barr virus infection of synovial membranes in patients with rheumatoid arthritis
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Pannus extracts and/or cells and tissues from rheumatoid arthritis (RA) patients and controls were tested for the presence of RA-associated nuclear antigen (RANA), anti-RANA, Epstein-Barr virus (EBV)-specific antigens, and EBV genomes. Using our present rather insensitive methods, RANA was rarely de
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