## Abstract 3,5‐Dichloroaniline is commonly found in many compounds with pharmacological and other biological activities. [^13^C~6~]‐Aniline or its hydrochloride salt was converted in three steps to [^13^C~6~]‐3,5‐dichloroaniline, which can be incorporated in compounds of interest and used as inter
An efficient synthesis of 5-(phenyl-13C6)-5-phenylhydantoin
✍ Scribed by Jacques H. Poupaert; Martial Winand; P. Dumont
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 129 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A procedure is described to convert benzene‐ ^13^C~6~ into 5‐(phenyl‐ ^13^C~6~)‐5‐phenylhydantoin in 80% overall yield.
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## Abstract Nefopam hydrochloride (I), an analgesic agent, was labelled with carbon‐13 at C‐1,3,4 and 6 positions for metabolic studies. The starting materials for the synthesis included commercially available phthalic acid‐carboxyl‐^13^C~1~ (II) and 2‐methylaminoethyl‐1,2‐^13^C~2~ alcohol. The ext
## Abstract 5‐[4,5‐^13^C~2~]‐ and 5‐[1,5‐^13^C~2~]Aminolevulinic acid (ALA) have been synthesized by the Gabriel condensation of potassium phthalimide with ethyl bromo[1,2‐^13^C~2~]acetate (derived from [1,2‐^13^C~2~]acetic acid) or ethyl bromo[2‐^13^C]‐acetate (derived from sodium [2‐^13^C]acetate