ChemInform Abstract: An Asymmetric Synth
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B. M. TROST; G. R. COOK
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Article
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2010
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John Wiley and Sons
⚖ 31 KB
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An Asymmetric Synthesis (-)-Epibatidine. -The title compound (X) is synthesized with a view to its biological activity and its low natural abundance. Key steps in this synthesis are the Pd-catalyzed desymmetrization of the dibenzoate (I) and the Pd-catalyzed cross coupling of the vinyl bromide (V)