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An asymmetric synthesis (−)-epibatidine

✍ Scribed by Barry M. Trost; Gregory R. Cook


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
231 KB
Volume
37
Category
Article
ISSN
0040-4039

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ChemInform Abstract: An Asymmetric Synth
✍ B. M. TROST; G. R. COOK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

An Asymmetric Synthesis (-)-Epibatidine. -The title compound (X) is synthesized with a view to its biological activity and its low natural abundance. Key steps in this synthesis are the Pd-catalyzed desymmetrization of the dibenzoate (I) and the Pd-catalyzed cross coupling of the vinyl bromide (V)