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ChemInform Abstract: Total Synthesis of (-)-Epibatidine Using an Asymmetric Diels—Alder Reaction with a Chiral N-Acylnitroso Dienophile.

✍ Scribed by Sakae Aoyagi; Ryuta Tanaka; Masaichi Naruse; Chihiro Kibayashi


Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
30
Category
Article
ISSN
0931-7597

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The First Enantioselective Aza-Diels-Alder Reactions of Imino Dienophiles on Use of a Chiral Zirconium Catalyst. -The first examples of catalytic, enantioselective DA reactions of imine dienophiles with Danishefsky's dienes are reported. The free hydroxyl group of the aldimines is crucial with resp