ChemInform Abstract: A Highly Diastereos
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E. CEULEMANS; M. VOETS; S. EMMERS; W. DEHAEN
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Article
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2010
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John Wiley and Sons
⚖ 34 KB
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The pyrazole aldehyde (I) undergoes Knoevenagel condensations with heterocycles to yield adducts, which are directly thermolyzed to cyclize via hetero Diels-Alder reactions to cis-fused tetracyclic title heterocycles. Interestingly, the isoxazolo-fused cycloadduct (VII) is converted to the spiro-azi