𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An approach to the synthesis of neplanocin A

✍ Scribed by Faith, William C.; Booth, Carlye A.; Foxman, Bruce M.; Snider, Barry B.


Book ID
126227652
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
420 KB
Volume
50
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Total synthesis of (βˆ’)-neplanocin A
✍ Mu-Ill Lim; Victor E Marquez πŸ“‚ Article πŸ“… 1983 πŸ› Elsevier Science 🌐 French βš– 228 KB

A total synthesis of (-)-neplanocin A has been accomplished in 15 steps starting from the readily available D-(+)-ribonic acid y-lactone. The neplanocin antibiotics (NPC-A, 6, C, D, and F) were isolated in 1979 from the culture filtrate of ampullariella regularis A11079.2 Of all the active neplanoci

Total Synthesis of Neplanocin A
✍ Michael Jung; Gustav OffenbΓ€cher; JΓ‘nos RΓ©tey πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 German βš– 459 KB

## Abstract The first total synthesis of racemic neplanocin A **(1)**After submitting our paper we learned that __Arita et al.__ [J. Am. Chem. Soc.105, 4049(1983)] synthesized the natural enantioner of Neplanocin A. from cyclopentadiene and acylnitroso‐3,5‐dinitrobenzoic acid is described. The syn

Total synthesis of (-)-neplanocin A
✍ Marquez, Victor E.; Lim, Mu Ill; Tseng, Christopher K. H.; Markovac, Anica; Prie πŸ“‚ Article πŸ“… 1988 πŸ› American Chemical Society 🌐 English βš– 880 KB
A concise synthesis of (βˆ’)-neplanocin A
✍ Naoyuki Yoshida; Takashi Kamikubo; Kunio Ogasawara πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 115 KB
Synthesis of the carbocyclic nucleoside
✍ John R Medich; Kevin B Kunnen; Carl R Johnson πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 214 KB

Neplanocin A has been prepared in 14 steps from cyclopentadiene (11% overall yield). The recent attention directed at the synthesis of compounds for the treatment of viral infections has resulted in a large number of nucleoside analogues displaying antiviral activity. Neplanocin A (NPC-A) 1, a nat