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Total synthesis of (-)-neplanocin A

✍ Scribed by Marquez, Victor E.; Lim, Mu Ill; Tseng, Christopher K. H.; Markovac, Anica; Priest, Matthew A.; Khan, M. Sami; Kaskar, Bashir

Book ID
124102442
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
880 KB
Volume
53
Category
Article
ISSN
0022-3263

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Total synthesis of (−)-neplanocin A
Total synthesis of (−)-neplanocin A
✍ Mu-Ill Lim; Victor E Marquez 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 228 KB

A total synthesis of (-)-neplanocin A has been accomplished in 15 steps starting from the readily available D-(+)-ribonic acid y-lactone. The neplanocin antibiotics (NPC-A, 6, C, D, and F) were isolated in 1979 from the culture filtrate of ampullariella regularis A11079.2 Of all the active neplanoci

Total Synthesis of Neplanocin A
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✍ Michael Jung; Gustav Offenbächer; János Rétey 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 German ⚖ 459 KB

## Abstract The first total synthesis of racemic neplanocin A **(1)**After submitting our paper we learned that __Arita et al.__ [J. Am. Chem. Soc.105, 4049(1983)] synthesized the natural enantioner of Neplanocin A. from cyclopentadiene and acylnitroso‐3,5‐dinitrobenzoic acid is described. The syn

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