๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Amino Acid-Derived Phthalimide and Saccharin Derivatives as Inhibitors of Human Leukocyte Elastase, Cathepsin G, and Proteinase 3

โœ Scribed by William C. Groutas; Lee S. Chong; Radhika Venkataraman; Rongze Kuang; Jeff B. Epp; Nadene Houser-Archield; He Huang; John R. Hoidal


Book ID
115566181
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
368 KB
Volume
332
Category
Article
ISSN
0003-9861

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


The Gabriel-Colman rearrangement in biol
โœ William C. Groutas; Lee S. Chong; Radhika Venkataraman; Jeffrey B. Epp; Rongze K ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 574 KB

Almtraet--The results of a structure-activity relationship study focusing on the interaction of a series of phthalimide and saccharin derivatives with leukocyte elastase, cathepsin G and proteinase 3 are described. The phthalimide derivatives were found to be inactive while some of the saccharin der

Design, synthesis, and in vitro inhibito
โœ William C. Groutas; Jeffrey B. Epp; Radhika Venkataraman; Rongze Kuang; Tien My ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 604 KB

The inhibitory activity toward human leukocyte elastase (HLE), cathepsin G (Cat G), and proteinase 3 (PR 3) of a series of saccharin derivatives having a sulfinate leaving group was investigated. The results of this study revealed that (a) inhibitory activity is dependent on the nature and pKa of th

Design, synthesis and biological evaluat
โœ William C. Groutas; Michael J. Brubaker; Lee S. Chong; Radhika Venkataraman; He ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 572 KB

Structure-activity relationship study and in vitro biochemical studies with human leukocyte elastase, cathepsin G and proteinase 3 were conducted using a series of succinimide derivatives.