✦ LIBER ✦

Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3

✍ Scribed by William C. Groutas; Michael J. Brubaker; Lee S. Chong; Radhika Venkataraman; He Huang; Jeffrey B. Epp; Rongze Kuang; John R. Hoidal

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 572 KB
Volume: 3
Category: Article
ISSN: 0968-0896
DOI: 10.1016/0968-0896(95)00024-b

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✦ Synopsis

Structure-activity relationship study and in vitro biochemical studies with human leukocyte elastase, cathepsin G and proteinase 3 were conducted using a series of succinimide derivatives.

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