Structure-activity relationship study and in vitro biochemical studies with human leukocyte elastase, cathepsin G and proteinase 3 were conducted using a series of succinimide derivatives.
โฆ LIBER โฆ
Isoxazoline derivatives as potential inhibitors of the proteolytic enzymes human leukocyte elastase, cathepsin G and proteinase 3: a structure-activity relationship study
โ Scribed by William C. Groutas; Radhika Venkataraman; Lee S. Chong; James E. Yoder; Jeffrey B. Epp; Michael A. Stanga; Eun-Hong Kim
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 330 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0968-0896
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Almtraet--The results of a structure-activity relationship study focusing on the interaction of a series of phthalimide and saccharin derivatives with leukocyte elastase, cathepsin G and proteinase 3 are described. The phthalimide derivatives were found to be inactive while some of the saccharin der