𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Efficient inhibition of human leukocyte elastase and cathepsin G by saccharin derivatives

✍ Scribed by Groutas, William C.; Houser-Archield, Nadene; Chong, Lee S.; Venkataraman, Radhika; Epp, Jeffrey B.; Huang, He; McClenahan, Jerald J.


Book ID
126087105
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
426 KB
Volume
36
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Design, synthesis, and in vitro inhibito
✍ William C. Groutas; Jeffrey B. Epp; Radhika Venkataraman; Rongze Kuang; Tien My πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 604 KB

The inhibitory activity toward human leukocyte elastase (HLE), cathepsin G (Cat G), and proteinase 3 (PR 3) of a series of saccharin derivatives having a sulfinate leaving group was investigated. The results of this study revealed that (a) inhibitory activity is dependent on the nature and pKa of th