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Alterations of the p16 gene in head and neck cancer: frequency and association with p53, PRAD-1 and HPV

โœ Scribed by Olshan, Andrew F; Weissler, Mark C; Pei, Hong; Conway, Kathleen; Anderson, Steven; Fried, Daniel B; Yarbrough, Wendell G


Book ID
110060540
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
639 KB
Volume
14
Category
Article
ISSN
0950-9232

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## Abstract The cellular tumor suppressor p16 is strongly overexpressed in cervical cancers and precancers. We have previously demonstrated that infiltrating T lymphocytes reactive against p16 can be found in cervical cancer patients. Here, we analyzed whether p16 induces humoral immune responses.