Overexpression of P53 in head and neck c
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David L. Watling; Dr. Allen M. Gown; Dr. Marc D. Coltrera
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Article
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1992
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John Wiley and Sons
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English
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The putative tumor suppressor gene p53 plays a key role in the regulation of cell proliferation. Functional loss of p53 protein through mutation or viral oncogene-complexing can result in p53 protein overexpression detectable by immunocytochemistry, which in turn has been associated with markers of