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Overexpression of the p53 gene in primary and metastatic head and neck carcinomas

✍ Scribed by Edward R. Sauter; John A. Ridge; Andres Klein-Szanto; Bruce Track; Deborah Cleveland; Karl V. Whitley; Rose M. Mohr


Book ID
115044596
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
380 KB
Volume
105
Category
Article
ISSN
0023-852X

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Overexpression of P53 in head and neck c
✍ David L. Watling; Dr. Allen M. Gown; Dr. Marc D. Coltrera πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 766 KB

The putative tumor suppressor gene p53 plays a key role in the regulation of cell proliferation. Functional loss of p53 protein through mutation or viral oncogene-complexing can result in p53 protein overexpression detectable by immunocytochemistry, which in turn has been associated with markers of