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Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma

✍ Scribed by Thomas K. Hoffmann; Eniko Sonkoly; Ulrich Hauser; Anke van Lierop; Theresa L. Whiteside; Jens Peter Klussmann; Dieter Hafner; Patrick Schuler; Ulrike Friebe-Hoffmann; Kathrin Scheckenbach; Kaisa Erjala; Reidar Grénman; Jörg Schipper; Henning Bier; Vera Balz

Book ID
113833013
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
170 KB
Volume
44
Category
Article
ISSN
1368-8375

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MicroRNA alterations in head and neck sq
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## Abstract MicroRNAs (mirs) are small noncoding RNA molecules (∼22 nucleotides) that regulate posttranscriptional gene expression. Currently, there has not been a comprehensive study of their role in primary head and neck squamous cell carcinoma (HNSCC). To determine the role of mirs in HNSCC, we