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HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer

✍ Scribed by Pernille Lassen; Jesper Grau Eriksen; Stephen Hamilton-Dutoit; Trine Tramm; Jan Alsner; Jens Overgaard


Book ID
118497546
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
354 KB
Volume
94
Category
Article
ISSN
0167-8140

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## Abstract The cellular tumor suppressor p16 is strongly overexpressed in cervical cancers and precancers. We have previously demonstrated that infiltrating T lymphocytes reactive against p16 can be found in cervical cancer patients. Here, we analyzed whether p16 induces humoral immune responses.