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Allelic variants of XRCC1 and XRCC3 repair genes and susceptibility of oral cancer in Brazilian patients

✍ Scribed by Mariana Bisarro dos Reis; Roberta Losi-Guembarovski; Enilze Maria de Souza Fonseca Ribeiro; Iglenir João Cavalli; Maria Celeste Morita; Gyl Henrique Albrecht Ramos; Benedito Valdecir de Oliveira; Lauro Toyoshi Mizuno; Silvia Regina Rogatto; Ilce Mara de Syllos Cólus


Book ID
114797284
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
116 KB
Volume
42
Category
Article
ISSN
0904-2512

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DNA repair gene XRCC2 and XRCC3 polymorp
✍ Simone Benhamou; Jarno Tuimala; Christine Bouchardy; Pierre Dayer; Alain Sarasin 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 71 KB 👁 1 views

## Abstract Cigarette smoke can generate reactive oxygen species, which are capable of inducing double‐strand breaks (DSBs) in DNA. Polymorphisms in __XRCC2__ and __XRCC3__ genes, involved in DSBs repair pathways, may alter an individual's susceptibility to smoking‐related cancers. We investigated