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Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan

✍ Scribed by Ching-Yu Yen; Shyun-Yeu Liu; Chung-Ho Chen; Hung-Fu Tseng; Li-Yeh Chuang; Cheng-Hong Yang; Ying-Chu Lin; Cheng-Hao Wen; Wei-Fan Chiang; Chang-Hsuan Ho; Hsiang-Chi Chen; Shaio-Ting Wang; Cheng-Wen Lin; Hsueh-Wei Chang

Book ID
111255100
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
110 KB
Volume
37
Category
Article
ISSN
0904-2512

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## Abstract Cigarette smoke can generate reactive oxygen species, which are capable of inducing double‐strand breaks (DSBs) in DNA. Polymorphisms in __XRCC2__ and __XRCC3__ genes, involved in DSBs repair pathways, may alter an individual's susceptibility to smoking‐related cancers. We investigated