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Alkaloid synthesis via the intramolecular imidate methylide 1,3-dipolar cycloaddition reaction

✍ Scribed by Richard Smith; Tom Livinghouse


Book ID
108374463
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
989 KB
Volume
41
Category
Article
ISSN
0040-4020

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Diastereoselective synthesis of nicotine
✍ Mehdi Ghandi; Abuzar Taheri; Alireza Abbasi πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 339 KB

## Abstract magnified image A simple diastereoselective route to nicotine derivatives is presented. The one‐pot three component 1,3‐dipolar cycloaddition reaction of the KnΓΆevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived __in situ__ from pyridin