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An expedient synthesis of epi-eburnamenine via an intramolecular 1,4-dipolar cycloaddition reaction

✍ Scribed by Albert Padwa; Mark A. Semones


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
172 KB
Volume
37
Category
Article
ISSN
0040-4039

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A short synthesis of (Β±)-alloyohimbane v
✍ Todd M. Heidelbaugh; Bing Liu; Albert Padwa πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 173 KB

Thioisomtinchnone dipoles were generated by the reaction of bromoalkenoyl chlorides with thioamides. The intramolecular dipolar-cycloaddition reaction was used for a short synthesis of the yohimbanoid alkaloid (+)-alloyohimbane.